2009-07-06: Vacant positions postdocs/assistant professor
Several academic positions (full-time) as researcher in molecular clinical cancer research are available at MDL. Application deadline September, 6th 2009.
Read full job announcement.
Project descriptions for bladder and prostate cancer positions.
Project descriptions for colon cancer positions. |
2009-06-25: Vacant position administrator
MDL offers a vacant position as an all-round research administrator, application deadline August 31, 2009.
Read more (Danish). |
2009-06-24: MDL is granted a 19.5 million Danish Kroner appropriation
We gladly announce that CMCC, The John and Birthe Meyer Cancer Center for Molecular and Clinical Cancer Research under the Dept. of Molecular Medicine, has received a major grant from the Meyer Foundation which assures continuation of our high-standard cancer research for the next five years.
CMCC's research focuses on molecular classification of cancer patients at high risk of disease and identification of patients with the most agressive tumours. To achieve this, the newest molecular technologies and extensive biobanks are applied.
Read more (Danish). |
2009-06-15: NormFinder software
We are happy to note a frequent use of our NormFinder software and a high number of inquiries. Therefore, we have updated the NormFinder documentation (v19) and created a sample data set, which better illustrates the use of the NormFinder software.
We hope to have answered frequently asked questions about group identifiers, data sheet organisation and evaluation of top ranked normalisation genes.
If you need more help, please use the information on the NormFinder page. |
2009-05-31: MDL research on "Cancer Research" cover
Associated professor Lars Dyrskjøt, who recently won a prize being "The most publishing researcher aged under 40 at Skejby Hospital", led the work on miRNAs in bladder cancer resulting in this publication:
Genomic profiling of microRNAs in bladder cancer: miR-129 is associated with poor outcome and promotes cell death in vitro. Dyrskjøt L, Ostenfeld MS, Bramsen JB, Silahtaroglu AN, Lamy P, Ramanathan R, Fristrup N, Jensen JL, Andersen CL, Zieger K, Kauppinen S, Ulhøi BP, Kjems J, Borre M, Orntoft TF. Cancer Res. 2009 Jun 1;69(11):4851-60.
Read more (in Danish).
See coverage by regional TV (Danish). |
2009-01-27: MOMA opening
The official opening of the novel Department of Molecular Medicine (MOMA) at Aarhus University Hospital Skejby takes place at March, 11th 2009.
MDL will be hosting a two-day symposium "Molecular Oncology" mainly aimed at PhD students and Postdocs in molecular cancer research to celebrate the inauguration of MOMA at March 12-13th, 2009.
invitation
program
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2008-11-19: MDL is moving
In december 2008 MDL will move to new locations at the Science Center Skejby (former residence of the newspaper Århus Stifstidende) nearby and belong to the new Department of Molecular Medicine (MOMA) at the Århus University Hospital Skejby.
The official opening will take place in march 2009.
MDL is going to enjoy spacious and modern facilities, which make room for state-of-the-art equipment and provide stimulating working surroundings for the staff.
New phone numbers from 16-12-2008:
Laboratory +45 8949 9430
Secretary +45 8949 9410
Read more about MOMA (Dept. of Molecular Medicine) in Danish |
2008-10-14: MDL's gentest for laktoseintolerans omtalt i Ugeskrift for Læger nr. 42

Mælkesukkerproblemer kan nu nemt bestemmes i en blodprøve
Mangelfuld optagelse af mælkesukker kan give luft i maven, mavesmerter og diare. Tidligere var det besværligt at teste personer for, om de havde problemer med mælkesukkeroptagelsen, men nu har forskerne fundet det gen, der bevirker, at man får disse problemer, og derfor kan det gøres ved en simpel blodprøve.
» Diagnosticering af laktoseintolerans hos voksne
» Leder: Laktoseintolerans - mælk og molekylærbiologi
» Laktoseintolerans
Download som pdf.
|
2008-09-11: Speciale Studerende i Kræftforskning
Hos Molekylær Diagnostisk Laboratorium, Klinisk Biokemisk
Afdeling, Skejby Sygehus arbejder vi med molekylær karakteristik
af blære-, prostata- og tarmkræft. Målet med forskningen
er at opnå en molekylær klassifikation af sygdommene
for dermed at kunne give en mere optimal behandling af patienterne.
Desuden er målet at opnå en større forståelse
af sygdommenes molekylære forhold i aktive pathways og i relation
til sygdomsforløb og behandlingsrespons.
Projektet vil tage udgangspunkt i molekylære forandringer
i tumorvæv som har en klinisk relevans. Det kan f.eks. være
microRNA eller mRNA transkript profiler som er relateret til udvikling
af metastaser eller respons på kemoterapi. Projektet vil bl.a.
involvere immunhistokemiske analyser, overudtryks- eller knockdown
analyser såvel som funktionelle assays til måling af
f.eks. apoptose, proliferation og invasionspotentiale efter in vitro
overudtryk eller knockdown af relevante molekyler. Relevante molekyler
vil blive udvalgt til klinisk afprøvning.
Er du interesseret i at lave speciale inden for kræftforskning
og indgå i et spændende forskermiljø så
kontakt Karin Demtröder på tlf. 8949-5119 eller Professor
Torben Ørntoft på tlf. 8949-5100.
Du kan læse mere om vores aktuelle forskning på www.mdl.dk
Du kan læse mere her Her |
2007-09-04:
Gentest forudsiger skæbnen for blærekræftpatienter |
|
 |
Forskere fra Skejby Sygehus
har udviklet en genchip, som kan afsløre, hvor slemt
blærekræftpatienter er ramt af deres sygdom. Det
viser en ny undersøgelse, hvor fire lande udover Danmark
har deltaget. Et stort skridt på vejen til, at chippen
kan blive en naturlig del af hospitalsgangen og hjælpe
til, at blærekræftpatienter får den bedste
og mest nænsomme behandling.
|
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| Læs den fulde
artikel her |
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2007-03-19: Updated Request Form
The request form for diagnostic genetical analysises has been updated
to version 8, please download from
www.mdl.dk/rekvisition.pdf. |
2007-03-12:
MDL 10-year anniversary
On May, 1st 1997 MDL was officially founded. The 10-year anniversary
will be celebrated on April, 27th. |
2007-02-26: Updated Request Form
The request form for diagnostic genetical analysises has been updated,
please download from
www.mdl.dk/rekvisition.pdf. |
| 2007-02-21: Vacant positions
MDL has three open postdoc positions (3-years) in Clinical Molecular
Cancer Research. Applicants will be evaluated by a review committee
at Aarhus University, The Faculty of Health Sciences.
Read
job announcements (Danish)
Application deadline: March 19th, 2007 |
| 2006-12-04: Cells get old fighting cancer
 |
| Photo:
Kræftens Bekæmpelse |
International cooperation, led by the known researchers and spouses
Jirina Bartkova and Jiri Bartek at The Danish Cancer Society, Copenhagen,
and with Danish scientists from The Danish Cancer Society, MDL and
Rigshospitalet resulted in another publication in the recognized
journal Nature:
Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas
D, Issaeva N, Vassiliou LV, Kolettas E, Niforou K, Zoumpourlis VC,
Takaoka M, Nakagawa H, Tort F, Fugger K, Johansson F, Sehested M,
Andersen CL, Dyrskjot L, Orntoft T, Lukas J, Kittas C, Helleday
T, Halazonetis TD, Bartek J, Gorgoulis VG.
Oncogene-induced senescence is part of the tumorigenesis barrier
imposed by DNA damage checkpoints. Nature. 2006 Nov 30;444(7119):633-7.
PubMed
Read
more (in Danish) at the The Danish Cancer Society website. |
| 2006-09-27: Vacant position
for molecular biologist
MDL seeks a molecular biologist full-time (37 h/week). Application
deadline: 16th October 2006. Read
more (Danish)...
See job announcement
(in Danish)
|
2006-07-27: New research results within
colorectal cancer therapy
MDL contributed to results published in Nature Genetics,
that inflict the therapy of colorectal cancer with HDAC inhibitors.
In the future, an individual test for a certain mutation can decide
if HDAC-inhibition therapy is useful or not.
Ropero S, Fraga MF, Ballestar E, Hamelin R, Yamamoto H,
Boix-Chornet M, Caballero R, Alaminos M, Setien F, Paz MF, Herranz
M, Palacios J, Arango D, Orntoft TF, Aaltonen LA, Schwartz S, Esteller
M. A truncating mutation of HDAC2 in human cancers confers
resistance to histone deacetylase inhibition. Nat Genet. 2006 May;38(5):566-9.
Epub 2006 Apr 16. PubMed
Read
this in Danish |
| 2006-06-28: MDL seeks
graduate student
The prostate cancer group at MDL seeks a graduate student (molecular
biology) for a master thesis project from September, 1st 2006:
"Characterization of a new tumour suppressor gene candidate
in prostate cancer by overexpression, siRNA knock-down and microarray
analysis"
Further information
 |
| 2006-05-17: MDL offers a new genetic analysis
A mutation screen for adult–type hypolactasia (LCT -13910C>T)
is offered in MDL's panel of diagnostic
services. Please refer to the Dep.
of Clinical Biochemistry for further information. A new requisition
form can be downloaded. |
| 2006-02-09:
MDL participates in ”The MicroRNA Research
Consortium – Towards novel molecular targets for LNA-based
cancer therapy”
The Danish
High Technology Fund under the Ministry of Science has granted
10 million Danish Kroner for the development of diagnostic techniques
to measure microRNA. The consortium consists of The University of
Copenhagen, Aarhus University Hospital (MDL), Bioneer, Exiqon, Visiopharm
and Novo Nordisk including Steno Diabetes Center. Together with
the investements of the participants the budget will be 32 million
Danish Kroner over three years. A kick-off meeting will be held
soon. Read
more (in Danish)... |
2006-01-24: MDL comments on breakthrough
in prostate cancer research
American researchers have published results in Science
that show chromosomal changes in 80% of prostate cancer patients,
a fusion of the TMPRSS2 and ETS transcription factor genes. These
results have implications in the development of carcinomas and the
molecular diagnosis and treatment of prostate cancer.
Niels Tørring, Ph.d. and leader of MDL's prostate cancer
research group comments on the website of the Danish
Cancer Society (in Danish). |
| 2005-11-11: MDL passes
German External Quality Assessment scheme with full marks
MDL participated in an External
Quality Assessment (EQA) program for molecular diagnostics of HNPCC
2005 in Bonn and München, Germany. Participants included
12 German members of "Berufsverband
Deutscher Humangenetiker e.V." and HNPCC centres supported
by the German Cancer Aid as well as four laboratories from abroad.
Nine laboratories including MDL achieved the maximum 18 points for
mutational analysis by sequencing, MLPA and DHPLC, interpretation
and written report to the counselling physician evaluating the results
and diagnostics possibilities/recommendation for family members
of the screened patient. |
2005-08-22: GEO data available
Download
our microarray raw data directly for selected publications using
the GENE EXPRESSION
OMNIBUS (GEO) database at NCBI.
See under supplementary data.
|
| 2005-06-21:
MDL in "Augustus"
MDL's research is covered by an article in the latest
issue of Århus University's alumne magazine "Augustus"
(page 20, in Danish). |
| 2005-05-23: Prof. T. Ørntoft receives
award
The
"Consul Ernst Carlsen Honorary Award" of 60.000 Danish
Kroner for excellent cancer research and humanitarian achievements,
carried out by prof. Torben Ørntoft and his research group
at MDL, was given to prof. Torben Ørntoft at monday. The
award is granted by a committee consisting of representatives from
Danish Universities.
Read more in Danish... |
2005-04-14: Research results
from MDL on "Nature" cover 
Danish cancer researchers from The Danish Cancer Society,
MDL and researchers from Institutes in Norway and the Czech Republic
have published the articel: "DNA
damage response as a candidate anti-cancer barrier in early human
tumorigenesis" in the recognized scientific journal "Nature"
today.
See also comments in 'News and Views' in the same issue: "Aborting
the birth of cancer".
Read more (in Danish) from Aarhus
University Hospital, The
Danish Cancer Society and see this news on the Danish
National TV. |
2005-04-04: Request form for
genetic analysis
To order genetic analysis service, please
use this request
form (in Danish). |
2005-03-01:
Center for Molecular Cancer Research CMCC,
a John and Birthe Meyer Cancer Center, will be officially opened at
March, 3rd at the Science Park at Skejby Hospital. |
| 2005-02-01: NormFinder
software
A new version of NormFinder for R and version 0.953 of the MS Excel
add-in are now available for direct download.
|
2004-11-02: Job announcements
MDL has vacant positions in Clinical Molecular Cancer Research as
researcher or group leader.
Application deadline is by November, 19th, 2004. |
2004-08-23: NormFinder software NormFinder
- a new MS Excel add-in for normalization of real-time quantitative
RT-PCR data developed by MDL. |
2004-08-10: Symposium announcement
The Third Symposium on Array Technology in Research and Diagnostics
will be held from October, 29th to 30th, 2004 at the Aarhus University
Hospital, Skejby. |
2004-06-22: MDL receives major funding
MDL has received a major donation of The John and Birthe Meyer Foundation
of 19.8 million Danish Kroner (about 2,6 mill. Euro) to strengthen
and enhance its research in bladder, colon and prostate cancer. A
new Center for Molecular Clinical Cancer
Research will be founded at Aarhus University Hospital at Skejby
in January 2005. MDL will cooperate with clinical and surgical departments
from different hospitals as well as research laboratories at Aarhus
University to gather and investigate numerous tumor samples. Read
this in Danish |