Birkenkamp-Demtroder,K., Christensen,L.L., Olesen,S.H., Frederiksen,C.M., Laiho,P., Aaltonen,L.A., Laurberg,S., Sorensen,F.B., Hagemann,R., Orntoft,T.F. Gene expression in colorectal cancer. Cancer Res.. 62(15): 4352-4363. 2002. PubMed

Celis,J.E., Celis,P., Palsdottir,H., Ostergaard,M., Gromov,P., Primdahl,H., Orntoft,T.F., Wolf,H., Celis,A., Gromova,I. Proteomic strategies to reveal tumor heterogeneity among urothelial papillomas. Mol.Cell Proteomics.. 1(4): 269-279. 2002. PubMed

Christensen,M., Katballe,N., Wikman,F., Primdahl,H., Sorensen,F.B., Laurberg,S., Orntoft,T.F. Antibody-based screening for hereditary nonpolyposis colorectal carcinoma compared with microsatellite analysis and sequencing. Cancer. 95(11): 2422-2430. 2002. PubMed

De Vos,J., Thykjaer,T., Tarte,K., Ensslen,M., Raynaud,P., Requirand,G., Pellet,F., Pantesco,V., Reme,T., Jourdan,M., Rossi,J.F., Orntoft,T., Klein,B. Comparison of gene expression profiling between malignant and normal plasma cells with oligonucleotide arrays. Oncogene. 21(44): 6848-6857. 2002. PubMed

Flamez,D., Berger,V., Kruhoffer,M., Orntoft,T., Pipeleers,D., Schuit,F.C. Critical role for cataplerosis via citrate in glucose-regulated insulin release. Diabetes. 51(7): 2018-2024. 2002. PubMed

Hilpert,J., Wogensen,L., Thykjaer,T., Wellner,M., Schlichting,U., Orntoft,T.F., Bachmann,S., Nykjaer,A., Willnow,T.E. Expression profiling confirms the role of endocytic receptor megalin in renal vitamin D3 metabolism. Kidney Int.. 62(5): 1672-1681. 2002. PubMed

Katballe,N., Christensen,M., Wikman,F.P., Orntoft,T.F., Laurberg,S. Frequency of hereditary non-polyposis colorectal cancer in Danish colorectal cancer patients. Gut. 50(1): 43-51. 2002. PubMed

Kennan,A., Aherne,A., Palfi,A., Humphries,M., McKee,A., Stitt,A., Simpson,D.A., Demtroder,K., Orntoft,T., Ayuso,C., Kenna,P.F., Farrar,G.J., Humphries,P. Identification of an IMPDH1 mutation in autosomal dominant retinitis pigmentosa (RP10) revealed following comparative microarray analysis of transcripts derived from retinas of wild-type and Rho(-/-) mice. Hum.Mol.Genet.. 11(5): 547-557. 2002. PubMed

Liang,G., Gonzales,F.A., Jones,P.A., Orntoft,T.F., Thykjaer,T. Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine. Cancer Res.. 62(4): 961-966. 2002. PubMed

Lu,M.L., Wikman,F., Orntoft,T.F., Charytonowicz,E., Rabbani,F., Zhang,Z., Dalbagni,G., Pohar,K.S., Yu,G., Cordon-Cardo,C. Impact of alterations affecting the p53 pathway in bladder cancer on clinical outcome, assessed by conventional and array-based methods. Clin.Cancer Res.. 8(1): 171-179. 2002. PubMed

Orntoft,T.F., Thykjaer,T., Waldman,F.M., Wolf,H., Celis,J.E. Genome-wide study of gene copy numbers, transcripts, and protein levels in pairs of non-invasive and invasive human transitional cell carcinomas. Mol.Cell Proteomics.. 1(1): 37-45. 2002. PubMed

Primdahl,H., von der,Maase H., Christensen,M., Wolf,H., Orntoft,T.F. Allelic deletions of Rb and L-myc in urine sediments from patients with bladder tumors or carcinoma in situ. Oncol.Rep.. 9(3): 551-555. 2002. PubMed

Primdahl,H., von der,Maase H., Sorensen,F.B., Wolf,H., Orntoft,T.F. Immunohistochemical study of the expression of cell cycle regulating proteins at different stages of bladder cancer. J.Cancer Res.Clin.Oncol.. 128(6): 295-301. 2002. PubMed

Primdahl,H., Wikman,F.P., von der,Maase H., Zhou,X.G., Wolf,H., Orntoft,T.F. Allelic imbalances in human bladder cancer: genome-wide detection with high-density single-nucleotide polymorphism arrays. J.Natl.Cancer Inst.. 94(3): 216-223. 2002. PubMed Suppl data

Spicker,J.S., Wikman,F., Lu,M.L., Cordon-Cardo,C., Workman,C., Orntoft,T.F., Brunak,S., Knudsen,S. Neural network predicts sequence of TP53 gene based on DNA chip. Bioinformatics.. 18(8): 1133-1134. 2002. PubMed

Tarte,K., De Vos,J., Thykjaer,T., Zhan,F., Fiol,G., Costes,V., Reme,T., Legouffe,E., Rossi,J.F., Shaughnessy,J.,Jr., Orntoft,T.F., Klein,B. Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts. Blood. 100(4): 1113-1122. 2002. PubMed

Vermijlen,D., Luo,D., Kruhoffer,M., Orntoft,T.F., Kuppen,P.J., Wisse,E. Is the presence of interleukin-2 receptor alpha in the serum of colorectal liver metastases patients derived from hepatic natural killer cells?. Cancer Immunol.Immunother.. 51(5): 291-292. 2002. PubMed

Cardozo,A.K., Kruhoffer,M., Leeman,R., Orntoft,T., Eizirik,D.L. Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays. Diabetes. 50(5): 909-920. 2001. PubMed

Cardozo,A.K., Heimberg,H., Heremans,Y., Leeman,R., Kutlu,B., Kruhoffer,M., Orntoft,T., Eizirik,D.L. A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells. J.Biol.Chem.. 276(52): 48879-48886. 2001. PubMed

Herbsleb,M., Knudsen,U.B., Orntoft,T.F., Bichel,P., Norrild,B., Knudsen,A., Mogensen,O. Telomerase activity, MIB-1, PCNA, HPV 16 and p53 as diagnostic markers for cervical intraepithelial neoplasia. APMIS. 109(9): 607-617. 2001. PubMed

Katballe,N., Bentzen,S.M., Christensen,M., Wikman,F.P., Orntoft,T., Laurberg,S. Role of chance in familial aggregation of colorectal cancer. Br.J.Cancer. 84(8): 1084-1086. 2001. PubMed

Katballe,N., Juul,S., Christensen,M., Orntoft,T.F., Wikman,F.P., Laurberg,S. Patient accuracy of reporting on hereditary non-polyposis colorectal cancer-related malignancy in family members. Br.J.Surg.. 88(9): 1228-1233. 2001. PubMed

Muller,W., Burgart,L.J., Krause-Paulus,R., Thibodeau,S.N., Almeida,M., Edmonston,T.B., Boland,C.R., Sutter,C., Jass,J.R., Lindblom,A., Lubinski,J., MacDermot,K., Sanders,D.S., Morreau,H., Muller,A., Oliani,C., Orntoft,T., Ponz,De Leon, Rosty,C., Rodriguez-Bigas,M., Ruschoff,J., Ruszkiewicz,A., Sabourin,J., Salovaara,R., Moslein,G. The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC)--results of an international collaborative study. Fam.Cancer. 1(2): 87-92. 2001. PubMed

Olesen,S.H., Thykjaer,T., Orntoft,T.F. Mitotic checkpoint genes hBUB1, hBUB1B, hBUB3 and TTK in human bladder cancer, screening for mutations and loss of heterozygosity. Carcinogenesis. 22(5): 813-815. 2001. PubMed Suppl data

Pedersen,M.W., Thykjaer,T., Orntoft,T.F., Damstrup,L., Poulsen,H.S. Profile of differentially expressed genes mediated by the type III epidermal growth factor receptor mutation expressed in a small-cell lung cancer cell line. Br.J.Cancer. 85(8): 1211-1218. 2001. PubMed

Thogersen,V.B., Sorensen,B.S., Poulsen,S.S., Orntoft,T.F., Wolf,H., Nexo,E. A subclass of HER1 ligands are prognostic markers for survival in bladder cancer patients. Cancer Res.. 61(16): 6227-6233. 2001. PubMed

Thykjaer,T., Christensen,M., Clark,A.B., Hansen,L.R., Kunkel,T.A., Orntoft,T.F. Functional analysis of the mismatch repair system in bladder cancer. Br.J.Cancer. 85(4): 568-575. 2001. PubMed

Thykjaer,T., Workman,C., Kruhoffer,M., Demtroder,K., Wolf,H., Andersen,L.D., Frederiksen,C.M., Knudsen,S., Orntoft,T.F. Identification of gene expression patterns in superficial and invasive human bladder cancer. Cancer Res.. 61(6): 2492-2499. 2001. PubMed Suppl data

Wyttenbach,A., Swartz,J., Kita,H., Thykjaer,T., Carmichael,J., Bradley,J., Brown,R., Maxwell,M., Schapira,A., Orntoft,T.F., Kato,K., Rubinsztein,D.C. Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease. Hum.Mol.Genet.. 10(17): 1829-1845. 2001. PubMed

Xiao,J., Gregersen,S., Kruhoffer,M., Pedersen,S.B., Orntoft,T.F., Hermansen,K. The effect of chronic exposure to fatty acids on gene expression in clonal insulin-producing cells: studies using high density oligonucleotide microarray. Endocrinology. 142(11): 4777-4784. 2001. PubMed

Celis,J.E., Kruhoffer,M., Gromova,I., Frederiksen,C., Ostergaard,M., Thykjaer,T., Gromov,P., Yu,J., Palsdottir,H., Magnusson,N., Orntoft,T.F. Gene expression profiling: monitoring transcription and translation products using DNA microarrays and proteomics. FEBS Lett.. 480(1): 2-16. 2000. PubMed

Christensen,L.L., Jensen,U.B., Bross,P., Orntoft,T.F. The C-terminal N-glycosylation sites of the human alpha1,3/4-fucosyltransferase III, -V, and -VI (hFucTIII, -V, adn -VI) are necessary for the expression of full enzyme activity. Glycobiology. 10(9): 931-939. 2000. PubMed

Christensen,L.L., Bross,P., Orntoft,T.F. Glycosylation of the N-terminal potential N-glycosylation sites in the human alpha1,3-fucosyltransferase V and -VI (hFucTV and -VI). Glycoconj.J.. 17(12): 859-865. 2000. PubMed

Christensen,M., Wolf,H., Orntoft,T.F. Microsatellite alterations in urinary sediments from patients with cystitis and bladder cancer. Int.J.Cancer. 85(5): 614-617. 2000. PubMed

Orntoft,I., Bonding,P. Choanal adenoid syndrome--a preliminary report. Acta Otolaryngol.Suppl. 543(365-5237): 220-221. 2000. PubMed

Pedersen,L.N., Kjaer,H.O., Moller,J.K., Orntoft,T.F., Ostergaard,L. High-resolution genotyping of Chlamydia trachomatis from recurrent urogenital infections. J.Clin.Microbiol.. 38(8): 3068-3071. 2000. PubMed

Primdahl,H., von der,Maase H., Christensen,M., Wolf,H., Orntoft,T.F. Allelic deletions of cell growth regulators during progression of bladder cancer. Cancer Res.. 60(23): 6623-6629. 2000. PubMed

Sengelov,L., Christensen,M., der Maase,H.D., Horn,T., Marcussen,N., Kamby,C., Orntoft,T. Loss of heterozygosity at 1p, 8p, 10p, 13q, and 17p in advanced urothelial cancer and lack of relation to chemotherapy response and outcome. Cancer Genet.Cytogenet.. 123(2): 109-113. 2000. PubMed

Tos,M., Orntoft,S., Stangerup,S.E. Results of tympanoplasty in children after 15 to 27 years. Ann.Otol.Rhinol.Laryngol.. 109(1): 17-23. 2000. PubMed

Tos,M., Stangerup,S.E., Orntoft,S. Reasons for reperforation after tympanoplasty in children. Acta Otolaryngol.Suppl. 543(365-5237): 143-146. 2000. PubMed

Wikman,F.P., Katballe,N., Christensen,M., Laurberg,S., Orntoft,T.F. Efficient mutation detection in mismatch repair genes using a combination of single-strand conformational polymorphism and heteroduplex analysis at a controlled temperature. Genet.Test.. 4(1): 15-21. 2000. PubMed

Wikman,F.P., Lu,M.L., Thykjaer,T., Olesen,S.H., Andersen,L.D., Cordon-Cardo,C., Orntoft,T.F. Evaluation of the performance of a p53 sequencing microarray chip using 140 previously sequenced bladder tumor samples. Clin.Chem.. 46(10): 1555-1561. 2000. PubMed Suppl data

Celis,J.E., Celis,P., Ostergaard,M., Basse,B., Lauridsen,J.B., Ratz,G., Rasmussen,H.H., Orntoft,T.F., Hein,B., Wolf,H., Celis,A. Proteomics and immunohistochemistry define some of the steps involved in the squamous differentiation of the bladder transitional epithelium: a novel strategy for identifying metaplastic lesions. Cancer Res.. 59(12): 3003-3009. 1999. PubMed

Celis,J.E., Ostergaard,M., Rasmussen,H.H., Gromov,P., Gromova,I., Varmark,H., Palsdottir,H., Magnusson,N., Andersen,I., Basse,B., Lauridsen,J.B., Ratz,G., Wolf,H., Orntoft,T.F., Celis,P., Celis,A. A comprehensive protein resource for the study of bladder cancer: http://biobase.dk/cgi-bin/celis. Electrophoresis. 20(2): 300-309. 1999. PubMed

Christensen,M., Sunde,L., Bolund,L., Orntoft,T.F. Comparison of three methods of microsatellite detection. Scand.J.Clin.Lab Invest. 59(3): 167-177. 1999. PubMed

Orntoft,T.F., Vestergaard,E.M. Clinical aspects of altered glycosylation of glycoproteins in cancer. Electrophoresis. 20(2): 362-371. 1999. PubMed

Ostergaard,M., Wolf,H., Orntoft,T.F., Celis,J.E. Psoriasin (S100A7): a putative urinary marker for the follow-up of patients with bladder squamous cell carcinomas. Electrophoresis. 20(2): 349-354. 1999. PubMed

Skorstengaard,K., Vestergaard,E.M., Langkilde,N.C., Christensen,L.L., Wolf,H., Orntoft,T.F. Lewis antigen mediated adhesion of freshly removed human bladder tumors to E-selectin. J.Urol.. 161(4): 1316-1323. 1999. PubMed

Thogersen,V.B., Jorgensen,P.E., Sorensen,B.S., Bross,P., Orntoft,T., Wolf,H., Nexo,E. Expression of transforming growth factor alpha and epidermal growth factor receptor in human bladder cancer. Scand.J.Clin.Lab Invest. 59(4): 267-277. 1999. PubMed

Vestergaard,E.M., Hein,H.O., Meyer,H., Grunnet,N., Jorgensen,J., Wolf,H., Orntoft,T.F. Reference values and biological variation for tumor marker CA 19-9 in serum for different Lewis and secretor genotypes and evaluation of secretor and Lewis genotyping in a Caucasian population. Clin.Chem.. 45(1): 54-61. 1999. PubMed

Bech,E., Andersen,H., Orntoft,T.F., Jakobsen,J. Association of IgM type anti-GM1 antibodies and muscle strength in chronic acquired demyelinating polyneuropathy. Ann.Neurol.. 43(1): 72-78. 1998. PubMed

Christensen,M., Jensen,M.A., Wolf,H., Orntoft,T.F. Pronounced microsatellite instability in transitional cell carcinomas from young patients with bladder cancer. Int.J.Cancer. 79(4): 396-401. 1998. PubMed

Mayer,M., Wilkinson,I., Heikkinen,R., Orntoft,T., Magid,E. Improved laboratory test selection and enhanced perception of test results as tools for cost-effective medicine. Clin.Chem.Lab Med.. 36(9): 683-690. 1998. PubMed

Orntoft,T.F., Wolf,H. Molecular alterations in bladder cancer. Urol.Res.. 26(4): 223-233. 1998. PubMed

Tos,M., Svendstrup,F., Arndal,H., Orntoft,S., Jakobsen,J., Borum,P., Schrewelius,C., Larsen,P.L., Clement,F., Barfoed,C., Romeling,F., Tvermosegaard,T. Efficacy of an aqueous and a powder formulation of nasal budesonide compared in patients with nasal polyps. Am.J.Rhinol.. 12(3): 183-189. 1998. PubMed

Vestergaard,E.M., Wolf,H., Orntoft,T.F. Increased concentrations of genotype-interpreted Ca 19-9 in urine of bladder cancer patients mark diffuse atypia of the urothelium. Clin.Chem.. 44(2): 197-204. 1998. PubMed

Vinter-Jensen,L., Orntoft,T.F. Glycoproteins in the urothelium and in the urine of the epidermal growth factor induced growing urinary tract in rats. Urol.Res.. 26(2): 97-103. 1998. PubMed 

Bech,E., Orntoft,T.F., Andersen,L.P., Skinhoj,P., Jakobsen,J. IgM anti-GM1 antibodies in the Guillain-Barre syndrome: a serological predictor of the clinical course. J.Neuroimmunol.. 72(1): 59-66. 1997. PubMed

Nielsen,H., Orntoft,S., Nielsen,T.G. Change in minimal cross sectional area using the new nasal dilator, "Airplus". Acta Otolaryngol.Suppl. 529(365-5237): 130-132. 1997. PubMed

Orntoft,T.F., Jepsen,J., Hansen,P.V., Raundahl,U., Langkilde,N.C. A two-site lectinoenzymatic assay for determination of tumour marker glycoproteins in rectal secretions. Glycoconj.J.. 14(2): 191-199. 1997. PubMed

Ostergaard,M., Rasmussen,H.H., Nielsen,H.V., Vorum,H., Orntoft,T.F., Wolf,H., Celis,J.E. Proteome profiling of bladder squamous cell carcinomas: identification of markers that define their degree of differentiation. Cancer Res.. 57(18): 4111-4117. 1997. PubMed

Celis,J.E., Ostergaard,M., Basse,B., Celis,A., Lauridsen,J.B., Ratz,G.P., Andersen,I., Hein,B., Wolf,H., Orntoft,T.F., Rasmussen,H.H. Loss of adipocyte-type fatty acid binding protein and other protein biomarkers is associated with progression of human bladder transitional cell carcinomas. Cancer Res.. 56(20): 4782-4790. 1996. PubMed

Celis,J.E., Rasmussen,H.H., Vorum,H., Madsen,P., Honore,B., Wolf,H., Orntoft,T.F. Bladder squamous cell carcinomas express psoriasin and externalize it to the urine. J.Urol.. 155(6): 2105-2112. 1996. PubMed

Mantoni,M., Larsen,P., Hansen,H., Tos,M., Berner,B., Orntoft,S. Coronal CT of the paranasal sinuses before and after functional endoscopic sinus surgery. Eur.Radiol.. 6(6): 920-924. 1996. PubMed

Orntoft,T.F., Vestergaard,E.M., Holmes,E., Jakobsen,J.S., Grunnet,N., Mortensen,M., Johnson,P., Bross,P., Gregersen,N., Skorstengaard,K., Jensen,U.B., Bolund,L., Wolf,H. Influence of Lewis alpha1-3/4-L-fucosyltransferase (FUT3) gene mutations on enzyme activity, erythrocyte phenotyping, and circulating tumor marker sialyl-Lewis a levels. J.Biol.Chem.. 271(50): 32260-32268. 1996. PubMed

Orntoft,T.F., Meldgaard,P., Pedersen,B., Wolf,H. The blood group ABO gene transcript is down-regulated in human bladder tumors and growth-stimulated urothelial cell lines. Cancer Res.. 56(5): 1031-1036. 1996. PubMed

Rasmussen,H.H., Orntoft,T.F., Wolf,H., Celis,J.E. Towards a comprehensive database of proteins from the urine of patients with bladder cancer. J.Urol.. 155(6): 2113-2119. 1996. PubMed

Vinter-Jensen,L., Smerup,M., Jorgensen,P.E., Juhl,C.O., Orntoft,T., Poulsen,S.S., Nexo,E. Chronic treatment with epidermal growth factor stimulates growth of the urinary tract in the rat. Urol.Res.. 24(1): 15-21. 1996. PubMed