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Fusco,A., Melillo,R.M., Santoro,M. Autocrine stimulation by osteopontin plays
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Fusco,A., Santoro,M., Melillo,R.M. Functional expression of the CXCR4 chemokine
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Cheng,J.C., Yoo,C.B., Weisenberger,D.J., Chuang,J., Wozniak,C.,
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Dyrskjot,L., Kruhoffer,M., Thykjaer,T.,
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Ewald,H., Wikman,F.P., Teruel,B.M., Buttenschon,H.N., Torralba,M., Als,T.D.,
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Mors,O. A genome-wide search for risk genes using homozygosity mapping and microarrays
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Grove,E.L., Orntoft,T.F., Lassen,J.F.,
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Lardon,J., De Breuck,S., Rooman,
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Wollheim,C., Jorgensen,M.C., Nerup,J., Karlsen,A.E. Gene expression profiles during beta cell maturation and after IL-1beta
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Vermijlen,D., Seynaeve,C., Luo,D.,
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Cardozo,A.K., Berthou,L., Kruhoffer,M., Orntoft,T., Nicolls,M.R., Eizirik,D.L. Gene microarray study corroborates proteomic findings in rodent islet cells. J.Proteome.Res.. 2(5): 553-555. 2003. PubMed
Celis,J.E., Gromov,P., Gromova,I., Moreira,J.M., Cabezon,T., Ambartsumian,N., Grigorian,M., Lukanidin,E., Thor,Straten P., Guldberg,P., Bartkova,J., Bartek,J., Lukas,J., Lukas,C., Lykkesfeldt,A., Jaattela,M., Roepstorff,P., Bolund,L., Orntoft,T., Brunner,N., Overgaard,J., Sandelin,K., Blichert-Toft,M., Mouridsen,H., Rank,F.E. Integrating Proteomic and Functional Genomic Technologies in Discovery-driven Translational Breast Cancer Research. Mol.Cell Proteomics.. 2(6): 369-377. 2003. PubMed
Dyrskjot,L., Thykjaer,T., Kruhoffer,M., Jensen,J.L., Marcussen,N., Hamilton-Dutoit,S., Wolf,H., Orntoft,T.F. Identifying distinct classes of bladder carcinoma using microarrays. Nat.Genet.. 33(1): 90-96. 2003. PubMed GEO data GSE88 GEO data GSE89
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Frederiksen,C.M., Knudsen,S., Laurberg,S., Orntoft,T.F. Classification of Dukes' B and C colorectal cancers using expression arrays. J.Cancer Res.Clin.Oncol.. 129(5): 263-271. 2003. PubMed
Hansen,L.T., Thykjaer,T., Orntoft,T.F., Rasmussen,L.J., Keller,P., Spang-Thomsen,M., Edmonston,T.B., Schmutte,C., Fishel,R., Petersen,L.N. The role of mismatch repair in small-cell lung cancer cells. Eur.J.Cancer. 39(10): 1456-1467. 2003. PubMed
Jagmohan-Changur,S., Poikonen,T., Vilkki,S., Launonen,V., Wikman,F., Orntoft,T.F., Moller,P., Vasen,H., Tops,C., Kolodner,R.D., Mecklin,J.P., Jarvinen,H., Bevan,S., Houlston,R.S., Aaltonen,L.A., Fodde,R., Wijnen,J., Karhu,A. EXO1 variants occur commonly in normal population: evidence against a role in hereditary nonpolyposis colorectal cancer. Cancer Res.. 63(1): 154-158. 2003. PubMed
Jeppesen,P.B., Gregersen,S., Rolfsen,S.E., Jepsen,M., Colombo,M., Agger,A., Xiao,J., Kruhoffer,M., Orntoft,T., Hermansen,K. Antihyperglycemic and blood pressure-reducing effects of stevioside in the diabetic Goto-Kakizaki rat. Metabolism. 52(3): 372-378. 2003. PubMed
Kutlu,B., Cardozo,A.K., Darville,M.I., Kruhoffer,M., Magnusson,N., Orntoft,T., Eizirik,D.L. Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells. Diabetes. 52(11): 2701-2719. 2003. PubMed
Laiho,P., Hienonen,T., Karhu,A., Lipton,L., Aalto,Y., Thomas,H.J., Birkenkamp-Demtroder,K., Hodgson,S., Salovaara,R., Mecklin,J.P., Jarvinen,H., Knuutila,S., Halford,S., Orntoft,T.F., Tomlinson,I., Launonen,V., Houlston,R., Aaltonen,L.A. Genome-wide allelotyping of 104 Finnish colorectal cancers reveals an excess of allelic imbalance in chromosome 20q in familial cases. Oncogene. 22(14): 2206-2214. 2003. PubMed
Moraes,R.C., Blondet,A., Birkenkamp-Demtroeder,K., Tirard,J., Orntoft,T.F., Gertler,A., Durand,P., Naville,D., Begeot,M. Study of the alteration of gene expression in adipose tissue of diet-induced obese mice by microarray and reverse transcription-polymerase chain reaction analyses. Endocrinology. 144(11): 4773-4782. 2003. PubMed
Nielsen,K., Birkenkamp-Demtroder,K., Ehlers,N., Orntoft,T.F. Identification of differentially expressed genes in keratoconus epithelium analyzed on microarrays. Invest Ophthalmol.Vis.Sci.. 44(6): 2466-2476. 2003. PubMed
Orntoft,T.F. [DNA microarrays (DNA chips) used in molecular medical research]. Ugeskr.Laeger. 165(8): 786-790. 2003. PubMed
Orntoft,T.F., Nielsen,O.S. [Comment to the article "Nepotism in peer review of applications for research grants"]. Ugeskr.Laeger. 165(48): 4638-4640. 2003. PubMed
Rasschaert,J., Liu,D., Kutlu,B., Cardozo,A.K., Kruhoffer,M., Orntoft,T.F., Eizirik,D.L. Global profiling of double stranded RNA- and IFN-gamma-induced genes in rat pancreatic beta cells. Diabetologia. 46(12): 1641-1657. 2003. PubMed
Sieber,O.M., Lipton,L., Crabtree,M., Heinimann,K., Fidalgo,P., Phillips,R.K., Bisgaard,M.L., Orntoft,T.F., Aaltonen,L.A., Hodgson,S.V., Thomas,H.J., Tomlinson,I.P. Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH. N.Engl.J.Med.. 348(9): 791-799. 2003. PubMed
Vallat,L., Magdelenat,H., Merle-Beral,H.,
Masdehors,P., Potocki,de Montalk, Davi,F., Kruhoffer,M., Sabatier,L.,
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Birkenkamp-Demtroder,K., Christensen,L.L., Olesen,S.H., Frederiksen,C.M., Laiho,P., Aaltonen,L.A., Laurberg,S., Sorensen,F.B., Hagemann,R., Orntoft,T.F. Gene expression in colorectal cancer. Cancer Res.. 62(15): 4352-4363. 2002. PubMed
Celis,J.E., Celis,P., Palsdottir,H., Ostergaard,M., Gromov,P., Primdahl,H., Orntoft,T.F., Wolf,H., Celis,A., Gromova,I. Proteomic strategies to reveal tumor heterogeneity among urothelial papillomas. Mol.Cell Proteomics.. 1(4): 269-279. 2002. PubMed
Christensen,M., Katballe,N., Wikman,F., Primdahl,H., Sorensen,F.B., Laurberg,S., Orntoft,T.F. Antibody-based screening for hereditary nonpolyposis colorectal carcinoma compared with microsatellite analysis and sequencing. Cancer. 95(11): 2422-2430. 2002. PubMed
De Vos,J., Thykjaer,T., Tarte,K., Ensslen,M., Raynaud,P., Requirand,G., Pellet,F., Pantesco,V., Reme,T., Jourdan,M., Rossi,J.F., Orntoft,T., Klein,B. Comparison of gene expression profiling between malignant and normal plasma cells with oligonucleotide arrays. Oncogene. 21(44): 6848-6857. 2002. PubMed
Flamez,D., Berger,V., Kruhoffer,M., Orntoft,T., Pipeleers,D., Schuit,F.C. Critical role for cataplerosis via citrate in glucose-regulated insulin release. Diabetes. 51(7): 2018-2024. 2002. PubMed
Hilpert,J., Wogensen,L., Thykjaer,T., Wellner,M., Schlichting,U., Orntoft,T.F., Bachmann,S., Nykjaer,A., Willnow,T.E. Expression profiling confirms the role of endocytic receptor megalin in renal vitamin D3 metabolism. Kidney Int.. 62(5): 1672-1681. 2002. PubMed
Katballe,N., Christensen,M., Wikman,F.P., Orntoft,T.F., Laurberg,S. Frequency of hereditary non-polyposis colorectal cancer in Danish colorectal cancer patients. Gut. 50(1): 43-51. 2002. PubMed
Kennan,A., Aherne,A., Palfi,A., Humphries,M., McKee,A., Stitt,A., Simpson,D.A., Demtroder,K., Orntoft,T., Ayuso,C., Kenna,P.F., Farrar,G.J., Humphries,P. Identification of an IMPDH1 mutation in autosomal dominant retinitis pigmentosa (RP10) revealed following comparative microarray analysis of transcripts derived from retinas of wild-type and Rho(-/-) mice. Hum.Mol.Genet.. 11(5): 547-557. 2002. PubMed
Liang,G., Gonzales,F.A., Jones,P.A., Orntoft,T.F., Thykjaer,T. Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine. Cancer Res.. 62(4): 961-966. 2002. PubMed
Lu,M.L., Wikman,F., Orntoft,T.F., Charytonowicz,E., Rabbani,F., Zhang,Z., Dalbagni,G., Pohar,K.S., Yu,G., Cordon-Cardo,C. Impact of alterations affecting the p53 pathway in bladder cancer on clinical outcome, assessed by conventional and array-based methods. Clin.Cancer Res.. 8(1): 171-179. 2002. PubMed
Orntoft,T.F., Thykjaer,T., Waldman,F.M., Wolf,H., Celis,J.E. Genome-wide study of gene copy numbers, transcripts, and protein levels in pairs of non-invasive and invasive human transitional cell carcinomas. Mol.Cell Proteomics.. 1(1): 37-45. 2002. PubMed
Primdahl,H., von der,Maase H., Christensen,M., Wolf,H., Orntoft,T.F. Allelic deletions of Rb and L-myc in urine sediments from patients with bladder tumors or carcinoma in situ. Oncol.Rep.. 9(3): 551-555. 2002. PubMed
Primdahl,H., von der,Maase H., Sorensen,F.B., Wolf,H., Orntoft,T.F. Immunohistochemical study of the expression of cell cycle regulating proteins at different stages of bladder cancer. J.Cancer Res.Clin.Oncol.. 128(6): 295-301. 2002. PubMed
Primdahl,H., Wikman,F.P., von der,Maase H., Zhou,X.G., Wolf,H., Orntoft,T.F. Allelic imbalances in human bladder cancer: genome-wide detection with high-density single-nucleotide polymorphism arrays. J.Natl.Cancer Inst.. 94(3): 216-223. 2002. PubMed Suppl data
Spicker,J.S., Wikman,F., Lu,M.L., Cordon-Cardo,C., Workman,C., Orntoft,T.F., Brunak,S., Knudsen,S. Neural network predicts sequence of TP53 gene based on DNA chip. Bioinformatics.. 18(8): 1133-1134. 2002. PubMed
Tarte,K., De Vos,J., Thykjaer,T., Zhan,F., Fiol,G., Costes,V., Reme,T., Legouffe,E., Rossi,J.F., Shaughnessy,J.,Jr., Orntoft,T.F., Klein,B. Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts. Blood. 100(4): 1113-1122. 2002. PubMed
Vermijlen,D.,
Luo,D., Kruhoffer,M., Orntoft,T.F., Kuppen,P.J., Wisse,E. Is the presence
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Cardozo,A.K., Kruhoffer,M., Leeman,R., Orntoft,T., Eizirik,D.L. Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays. Diabetes. 50(5): 909-920. 2001. PubMed
Cardozo,A.K., Heimberg,H., Heremans,Y., Leeman,R., Kutlu,B., Kruhoffer,M., Orntoft,T., Eizirik,D.L. A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells. J.Biol.Chem.. 276(52): 48879-48886. 2001. PubMed
Herbsleb,M., Knudsen,U.B., Orntoft,T.F., Bichel,P., Norrild,B., Knudsen,A., Mogensen,O. Telomerase activity, MIB-1, PCNA, HPV 16 and p53 as diagnostic markers for cervical intraepithelial neoplasia. APMIS. 109(9): 607-617. 2001. PubMed
Katballe,N., Bentzen,S.M., Christensen,M., Wikman,F.P., Orntoft,T., Laurberg,S. Role of chance in familial aggregation of colorectal cancer. Br.J.Cancer. 84(8): 1084-1086. 2001. PubMed
Katballe,N., Juul,S., Christensen,M., Orntoft,T.F., Wikman,F.P., Laurberg,S. Patient accuracy of reporting on hereditary non-polyposis colorectal cancer-related malignancy in family members. Br.J.Surg.. 88(9): 1228-1233. 2001. PubMed
Muller,W., Burgart,L.J., Krause-Paulus,R., Thibodeau,S.N., Almeida,M., Edmonston,T.B., Boland,C.R., Sutter,C., Jass,J.R., Lindblom,A., Lubinski,J., MacDermot,K., Sanders,D.S., Morreau,H., Muller,A., Oliani,C., Orntoft,T., Ponz,De Leon, Rosty,C., Rodriguez-Bigas,M., Ruschoff,J., Ruszkiewicz,A., Sabourin,J., Salovaara,R., Moslein,G. The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC)--results of an international collaborative study. Fam.Cancer. 1(2): 87-92. 2001. PubMed
Olesen,S.H., Thykjaer,T., Orntoft,T.F. Mitotic checkpoint genes hBUB1, hBUB1B, hBUB3 and TTK in human bladder cancer, screening for mutations and loss of heterozygosity. Carcinogenesis. 22(5): 813-815. 2001. PubMed Suppl data
Pedersen,M.W., Thykjaer,T., Orntoft,T.F., Damstrup,L., Poulsen,H.S. Profile of differentially expressed genes mediated by the type III epidermal growth factor receptor mutation expressed in a small-cell lung cancer cell line. Br.J.Cancer. 85(8): 1211-1218. 2001. PubMed
Thogersen,V.B., Sorensen,B.S., Poulsen,S.S., Orntoft,T.F., Wolf,H., Nexo,E. A subclass of HER1 ligands are prognostic markers for survival in bladder cancer patients. Cancer Res.. 61(16): 6227-6233. 2001. PubMed
Thykjaer,T., Christensen,M., Clark,A.B., Hansen,L.R., Kunkel,T.A., Orntoft,T.F. Functional analysis of the mismatch repair system in bladder cancer. Br.J.Cancer. 85(4): 568-575. 2001. PubMed
Thykjaer,T., Workman,C., Kruhoffer,M., Demtroder,K., Wolf,H., Andersen,L.D., Frederiksen,C.M., Knudsen,S., Orntoft,T.F. Identification of gene expression patterns in superficial and invasive human bladder cancer. Cancer Res.. 61(6): 2492-2499. 2001. PubMed Suppl data
Wyttenbach,A., Swartz,J., Kita,H., Thykjaer,T., Carmichael,J., Bradley,J., Brown,R., Maxwell,M., Schapira,A., Orntoft,T.F., Kato,K., Rubinsztein,D.C. Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease. Hum.Mol.Genet.. 10(17): 1829-1845. 2001. PubMed
Xiao,J.,
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Celis,J.E., Kruhoffer,M., Gromova,I., Frederiksen,C., Ostergaard,M., Thykjaer,T., Gromov,P., Yu,J., Palsdottir,H., Magnusson,N., Orntoft,T.F. Gene expression profiling: monitoring transcription and translation products using DNA microarrays and proteomics. FEBS Lett.. 480(1): 2-16. 2000. PubMed
Christensen,L.L., Jensen,U.B., Bross,P., Orntoft,T.F. The C-terminal N-glycosylation sites of the human alpha1,3/4-fucosyltransferase III, -V, and -VI (hFucTIII, -V, adn -VI) are necessary for the expression of full enzyme activity. Glycobiology. 10(9): 931-939. 2000. PubMed
Christensen,L.L., Bross,P., Orntoft,T.F. Glycosylation of the N-terminal potential N-glycosylation sites in the human alpha1,3-fucosyltransferase V and -VI (hFucTV and -VI). Glycoconj.J.. 17(12): 859-865. 2000. PubMed
Christensen,M., Wolf,H., Orntoft,T.F. Microsatellite alterations in urinary sediments from patients with cystitis and bladder cancer. Int.J.Cancer. 85(5): 614-617. 2000. PubMed
Orntoft,I., Bonding,P. Choanal adenoid syndrome--a preliminary report. Acta Otolaryngol.Suppl. 543(365-5237): 220-221. 2000. PubMed
Pedersen,L.N., Kjaer,H.O., Moller,J.K., Orntoft,T.F., Ostergaard,L. High-resolution genotyping of Chlamydia trachomatis from recurrent urogenital infections. J.Clin.Microbiol.. 38(8): 3068-3071. 2000. PubMed
Primdahl,H., von der,Maase H., Christensen,M., Wolf,H., Orntoft,T.F. Allelic deletions of cell growth regulators during progression of bladder cancer. Cancer Res.. 60(23): 6623-6629. 2000. PubMed
Sengelov,L., Christensen,M., der Maase,H.D., Horn,T., Marcussen,N., Kamby,C., Orntoft,T. Loss of heterozygosity at 1p, 8p, 10p, 13q, and 17p in advanced urothelial cancer and lack of relation to chemotherapy response and outcome. Cancer Genet.Cytogenet.. 123(2): 109-113. 2000. PubMed
Tos,M., Orntoft,S., Stangerup,S.E. Results of tympanoplasty in children after 15 to 27 years. Ann.Otol.Rhinol.Laryngol.. 109(1): 17-23. 2000. PubMed
Tos,M., Stangerup,S.E., Orntoft,S. Reasons for reperforation after tympanoplasty in children. Acta Otolaryngol.Suppl. 543(365-5237): 143-146. 2000. PubMed
Wikman,F.P., Katballe,N., Christensen,M., Laurberg,S., Orntoft,T.F. Efficient mutation detection in mismatch repair genes using a combination of single-strand conformational polymorphism and heteroduplex analysis at a controlled temperature. Genet.Test.. 4(1): 15-21. 2000. PubMed
Wikman,F.P., Lu,M.L., Thykjaer,T., Olesen,S.H., Andersen,L.D.,
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Skorstengaard,K., Vestergaard,E.M.,
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