Molecular Diagnostic Laboratory
Nordic Centre of Excellence in Molecular Medicine

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2008

According to JCR Science Edition 2008, the total impact factor of these 28 publications is 98 (3 journals not present), with 17 publications with an impact factor above 2.5.


Alhopuro P, Phichith D, Tuupanen S, Sammalkorpi H, Nybondas M, Saharinen J, Robinson JP, Yang Z, Chen LQ, Orntoft T, Mecklin JP, Järvinen H, Eng C, Moeslein G, Shibata D, Houlston RS, Lucassen A, Tomlinson IP, Launonen V, Ristimäki A, Arango D, Karhu A, Sweeney HL, Aaltonen LA.
Unregulated smooth-muscle myosin in human intestinal neoplasia.
Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5513-8. Epub 2008 Apr 7. PubMed

Braun CJ, Zhang X, Savelyeva I, Wolff S, Moll UM, Schepeler T, Ørntoft TF, Andersen CL, Dobbelstein M.
p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest.
Cancer Res. 2008 Dec 15;68(24):10094-104. PubMed

Bross P, Naundrup S, Hansen J, Nielsen MN, Christensen JH, Kruhøffer M, Palmfeldt J, Corydon TJ, Gregersen N, Ang D, Georgopoulos C, Nielsen KL.
The HSP60-(P.val98ile) mutation associated with hereditary spastic paraplegia SPG13 compromises chaperonin function both in vitro and in vivo.
J Biol Chem. 2008 Jun 6;283(23):15694-700. Epub 2008 Apr 8. PubMed

Christensen LL, Madsen BE, Wikman FP, Wiuf C, Koed K, Tjoennland A, Olsen A, Syvanen AC, Andersen CL, Orntoft TF.
The association between genetic variants in hMLH1 and hMSH2 and the development of sporadic colorectal cancer in the Danish population.
BMC Med Genet. 2008 Jun 11;9(1):52 [Epub ahead of print] PubMed

Ehlers N, Hjortdal J, Nielsen K, Thiel HJ, Ørntoft T.
Phenotypic variability in Meesmann's dystrophy: clinical review of the literature and presentation of a family genetically identical to the original family.
Acta Ophthalmol Scand. 2008 Feb;86(1):40-4. Epub 2007 Nov 6. Review. PubMed 

Heebøll S, Borre M, Ottosen PD, Andersen CL, Mansilla F, Dyrskjøt L, Orntoft TF, Tørring N.
SMARCC1 expression is upregulated in prostate cancer and positively correlated with tumour recurrence and dedifferentiation.
Histol Histopathol. 2008 Sep;23(9):1069-76. PubMed

Herbsleb M, Birkenkamp-Demtroder K, Thykjaer T, Wiuf C, Hein AM, Orntoft TF, Dyrskjøt L.
Increased cell motility and invasion upon knockdown of lipolysis stimulated lipoprotein receptor (LSR) in SW780 bladder cancer cells.
BMC Med Genomics. 2008 Jul 22;1:31. PubMed

Herbsleb M, Christensen OF, Thykjaer T, Wiuf C, Borre M, Orntoft TF, Dyrskjot L.
Bioinformatic identification of FGF, p38-MAPK, and calcium signalling pathways associated with carcinoma in situ in the urinary bladder.
BMC Cancer. 2008 Jan 31;8(1):37 [Epub ahead of print] PubMed

Jorissen RN, Lipton L, Gibbs P, Chapman M, Desai J, Jones IT, Yeatman TJ, East P, Tomlinson IP, Verspaget HW, Aaltonen LA, Kruhøffer M, Orntoft TF, Andersen CL, Sieber OM.
Links DNA copy-number alterations underlie gene expression differences between microsatellite stable and unstable colorectal cancers.
Clin Cancer Res. 2008 Dec 15;14(24):8061-9. PubMed

Kirkegaard I, Petersen OB, Uldbjerg N, Tørring N.
Improved performance of first-trimester combined screening for trisomy 21 with the double test taken before a gestational age of 10 weeks.
Prenat Diagn. 2008 Sep;28(9):839-44. PubMed

Mansilla F, da Costa KA, Wang S, Kruhøffer M, Lewin TM, Orntoft TF, Coleman RA, Birkenkamp-Demtröder K.
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) overexpression in human colorectal cancer.
J Mol Med. 2009 Jan;87(1):85-97. Epub 2008 Oct 31. PubMed

Mansilla F, Dominguez CA, Yeadon JE, Corydon TJ, Burden SJ, Knudsen CR.
Translation elongation factor eEF1A binds to a novel myosin binding protein-C-like protein.
J Cell Biochem. 2008 Oct 15;105(3):847-5. PubMed

Nilbert M, Wikman FP, Hansen TV, Krarup HB, Orntoft TF, Nielsen FC, Sunde L, Gerdes AM, Cruger D, Timshel S, Bisgaard ML, Bernstein I, Okkels H.
Major contribution from recurrent alterations and MSH6 mutations in the Danish Lynch syndrome population.
Fam Cancer. 2009;8(1):75-83. Epub 2008 Jun 20. PubMed 

Nielsen FC, Ørntoft TF; Dansk Selskab for Klinisk Biokemi.
[Genomic microarray technology. The Danish Society of Clinical Biochemistry]
Ugeskr Laeger. 2008 Mar 17;170(12):1037. Danish. No abstract available. PubMed 

Nielsen K, Orntoft T, Hjortdal J, Rasmussen T, Ehlers N.
A novel mutation as the basis for asymptomatic meesmann dystrophy in a Danish family.
Cornea. 2008 Jan;27(1):100-2. PubMed

Offenberg H, Brünner N,  Mansilla F,  Ørntoft TF and  Birkenkamp-Demtroder K.
TIMP-1 expression in human colorectal cancer is associated with TGF-B1, LOXL2, INHBA1, TNF-AIP6 and TIMP-2 transcript profiles.
Mol Oncol. 2008 Oct;2(3):233-40. Epub 2008 Jun 18. PubMed  

Reusens B, Sparre T, Kalbe L, Bouckenooghe T, Theys N, Kruhøffer M, Orntoft TF, Nerup J, Remacle C.
The intrauterine metabolic environment modulates the gene expression pattern in fetal rat islets: prevention by maternal taurine supplementation.
Diabetologia. 2008 May;51(5):836-45. Epub 2008 Mar 3. PubMed 

Sammalkorpi H, Alhopuro P, Niittymäki I, Orntoft TF, Hokland P, Karhu A, Aaltonen LA.
Mutation analysis of MYH11 in acute myeloid leukemia.
Leuk Lymphoma. 2008 Sep;49(9):1829-31. No abstract available. PubMed

Schepeler T, Reinert JT, Ostenfeld MS, Christensen LL, Silahtaroglu AN, Dyrskjøt L, Wiuf C, Sørensen FJ, Kruhøffer M, Laurberg S, Kauppinen S, Ørntoft TF, Andersen CL.
Diagnostic and prognostic microRNAs in stage II colon cancer.
Cancer Res. 2008 Aug 1;68(15):6416-24. PubMed

Spencer K, Cowans NJ, Uldbjerg N, Tørring N.
First-trimester ADAM12s as early markers of trisomy 21: a promise still unfulfilled?
Prenat Diagn. 2008 Apr;28(4):338-42. PubMed

Spencer K, Cowans NJ, Uldbjerg N, Vereecken A, Tørring N. First trimester intact hCG as an early marker of trisomy 21: a promise unrecognised? Prenat Diagn. 2008 Nov 12; [Epub ahead of print] PubMed

Sørensen KD, Borre M, Ørntoft TF, Dyrskjøt L, Tørring N.
Chromosomal deletion, promoter hypermethylation and downregulation of FYN in prostate cancer.
Int J Cancer. 2008 Feb 1;122(3):509-19. PubMed

Thorsen K, Sørensen KD, Brems-Eskildsen AS, Modin C, Gaustadnes M, Hein AM, Kruhøffer M, Laurberg S, Borre M, Wang K, Brunak S, Krainer AR, Tørring N, Dyrskjøt L, Andersen CL, Orntoft TF.
Alternative splicing in colon, bladder, and prostate cancer identified by exon-array analysis.
Mol Cell Proteomics. 2008 Jul;7(7):1214-24. Epub 2008 Mar 18. PubMed

Tørring N, Jølving LR, Petersen OB, Holmskov A, Hertz JM, Uldbjerg N.
[Prenatal diagnostics in Arhus and Viborg Counties after implementation of first trimester risk assessment] Ugeskr Laeger. 2008 Jan 7;170(1):50-4. Danish. PubMed

Obro NF, Lademann U, Birkenkamp-Demtroder K, Holten-Andersen L, Brünner N, Offenberg H.
A TIMP-1 splice variant transcript: Possible role in regulation of TIMP-1 expression.
Cancer Lett. 2008 Jan 2 [Epub ahead of print] PubMed  

Ørntoft TF, Dyrskjøt L. Gene signatures for risk-adapted treatment of bladder cancer. Scand J Urol Nephrol Suppl. 2008 Sep;(218):166-74. PubMed

Ortis F, Pirot P, Naamane N, Kreins AY, Rasschaert J, Moore F, Théâtre E, Verhaeghe C, Magnusson NE, Chariot A, Orntoft TF, Eizirik DL.
Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells.
Diabetologia. 2008 May 8; [Epub ahead of print] PubMed

Wang Y, Kowalski J, Tsai HL, Marik R, Prasad N, Somervell H, Lo PK, Sangenario LE, Dyrskjot L, Orntoft TF, Westra WH, Meeker AK, Eshleman JR, Umbricht CB, Zeiger MA.
Differentiating Alternative Splice Variant Patterns of Human Telomerase Reverse Transcriptase in Thyroid Neoplasms.
Thyroid. 2008 Sep 24; [Epub ahead of print] PubMed



Updated: 20 January, 2010

 
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