2009

Andersen CL, Christensen LL, Thorsen K, Schepeler T, Sorensen FB, Verspaget HW, Simon R, Kruhoffer M, Aaltonen LA, Laurberg S, Orntoft TF.
Dysregulation of the transcription factors SOX4, CBFB and SMARCC1 correlates with outcome of colorectal cancer.
Br J Cancer. 2009 Feb 10;100(3):511-23. Epub 2009 Jan 20. PubMed

Berchtold LA, Larsen CM, Vaag A, Faulenbach M, Workman CT, Kruhøffer M, Donath M, Mandrup-Poulsen T.
IL-1 receptor antagonism and muscle gene expression in patients with type 2 diabetes.
Eur Cytokine Netw. 2009 Jun 1;20(2):81-87. PubMed

Christensen LL, Kariola R, Korhonen MK, Wikman FP, Sunde L, Gerdes AM, Okkels H, Brandt CA, Bernstein I, Hansen TV, Hagemann-Madsen R, Andersen CL, Nyström M, Ørntoft TF.
Functional characterization of rare missense mutations in MLH1 and MSH2 identified in Danish colorectal cancer patients.
Fam Cancer. 2009;8(4):489-500. Epub 2009 Aug 21. PubMed

Dyrskjøt L, Ostenfeld MS, Bramsen JB, Silahtaroglu AN, Lamy P, Ramanathan R, Fristrup N, Jensen JL, Andersen CL, Zieger K, Kauppinen S, Ulhøi BP, Kjems J, Borre M, Ørntoft TF.
Genomic Profiling of MicroRNAs in Bladder Cancer; miR-129 Is Associated with Poor Outcome and Promotes Cell Death In vitro.
Cancer Research. 2009 Jun 1;69(11):4851-60. PubMed

Egerod FL, Bartels A, Fristrup N, Borre M, Orntoft TF, Oleksiewicz MB, Brunner N, Dyrskjot L.
High frequency of tumor cells with nuclear Egr-1 protein expression in human bladder cancer is associated with disease progression.
BMC Cancer. 2009 Oct 30;9(1):385. [Epub ahead of print] PubMed

Heebøll S, Borre M, Ottosen PD, Dyrskjøt L, Orntoft TF, Tørring N.
Snail1 is over-expressed in prostate cancer.
APMIS. 2009 Mar;117(3):196-204. PubMed

Hollegaard MV, Grauholm J, Borglum A, Nyegaard M, Norgaard-Pedersen B, Orntoft T, Mortensen PB, Wiuf C, Mors O, Didriksen M, Thorsen P, Hougaard DM.
Genome-wide scans using archived neonatal dried blood spot samples.
BMC Genomics. 2009 Jul 4;10(1):297. [Epub ahead of print] PubMed

Jensen SA, Vainer B, Kruhoffer M, Sorensen JB.
Microsatellite instability in colorectal cancer and association with thymidylate synthase and dihydropyrimidine dehydrogenase expression.
BMC Cancer. 2009 Jan 20;9:25. PubMed

Jorissen RN, Gibbs P, Christie M, Prakash S, Lipton L, Desai J, Kerr D, Aaltonen LA, Arango D, Kruhøffer M, Orntoft TF, Andersen CL, Gruidl M, Kamath VP, Eschrich S, Yeatman TJ, Sieber OM.
Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer.
Clin Cancer Res. 2009 Dec 8. [Epub ahead of print] PubMed

Mansilla F, Lamy P, Ørntoft TF, and Birkenkamp-Demtröder K.
Genes Involved in Human Ribosome Biogenesis are Transcriptionally Upregulated in Colorectal Cancer. Scholarly Research Exchange, vol. 2009, Article ID 657042, 2009. doi:10.3814/2009/657042

Mauvezin C, Orpinell M, Francis VA, Mansilla F, Duran J, Ribas V, Palacín M, Boya P, Teleman AA and Zorzano A.
The nuclear cofactor DOR regulates autophagy in mammalian and Drosophila cells.
EMBO reports. advance online publication 4 December 2009; doi:10.1038/embor.2009.242

Ortis F, Naamane N, Flamez D, Ladrière L, Moore F, Cunha DA, Colli ML, Thykjaer T, Thorsen K, Orntoft TF, Eizirik DL.
The cytokines IL-1{beta} and TNF-{alpha} regulate different transcriptional and alternative splicing networks in primary beta cells.
Diabetes. 2010 Feb;59(2):358-74. Epub 2009 Nov 23. PubMed

Ostenfeld MS, Bramsen JB, Lamy P, Villadsen SB, Fristrup N, Sørensen KD, Ulhøi B, Borre M, Kjems J, Dyrskjøt L, Orntoft TF.
miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors.
Oncogene. 2009 Nov 16. [Epub ahead of print] PubMed

Sørensen KD, Wild PJ, Mortezavi A, Adolf K, Tørring N, Heebøll S, Ulhøi BP, Ottosen P, Sulser T,
Hermanns T, Moch H, Borre M, Ørntoft TF and Dyrskjøt L.
Genetic and Epigenetic SLC18A2 Silencing in Prostate Cancer is an Independent Adverse Predictor of Biochemical Recurrence after Radical Prostatectomy.
Clin Cancer Res. 2009 Feb 15;15(4):1400-10. PubMed 

Zieger K, Marcussen N, Borre M, Ørntoft TF, Dyrskjøt L.
Consistent genomic alterations in carcinoma in situ of the urinary bladder confirm the presence of two major pathways in bladder cancer development.
Int J Cancer. 2009 Nov 1;125(9):2095-103. PubMed

Zieger K, Wiuf C, Jensen KM, Orntoft TF, Dyrskjot L.
Chromosomal imbalance in the progression of high-risk non-muscle invasive bladder cancer.
BMC Cancer. 2009 May 16;9(1):149. PubMed