2010

Alhopuro P, Björklund M, Sammalkorpi H, Turunen M, Tuupanen S, Biström M, Niittymäki I, Lehtonen HJ, Kivioja T, Launonen V, Saharinen J, Nousiainen K, Hautaniemi S, Nuorva K, Mecklin JP, Järvinen H, Orntoft T, Arango D, Lehtonen R, Karhu A, Taipale J, Aaltonen LA.
Mutations in the Circadian Gene CLOCK in Colorectal Cancer.
Mol Cancer Res. 2010 Jul;8(7):952-60. Epub 2010 Jun 15. PubMed

Andersen CL, Lamy P, Thorsen K, Kjeldsen E, Wikman F, Villesen P, Oster B, Laurberg S, Orntoft TF.Frequent genomic loss at chr16p13.2 is associated with poor prognosis in colorectal cancer.
Int J Cancer. 2010 Dec 10. [Epub ahead of print] PubMed

Brems-Eskildsen AS, Zieger K, Toldbod H, Holcomb C, Higuchi R, Mansilla F, Munksgaard PP, Borre M, Orntoft TF, Dyrskjot L.
Prediction and diagnosis of bladder cancer recurrence based on urinary content of hTERT, SENP1, PPP1CA, and MCM5 transcripts.
BMC Cancer. 2010 Nov 24;10(1):646. PubMed

Hansen RL, Heeboll S, Ottosen PD, Dyrskjøt L, Borre M.
Smarcc1 expression: a significant predictor of disease-specific survival in patients with clinically localized prostate cancer treated with no intention to cure.
Scand J Urol Nephrol. 2011 Mar;45(2):91-6. Epub 2010 Nov 18. PubMed

Lamy P, Wiuf C, Orntoft TF, Andersen CL.
Rseg - an R package to optimize segmentation of SNP array data.
Bioinformatics. 2011 Feb 1;27(3):419-20. Epub 2010 Dec 5. PubMed

Marteau JB, Rigaud O, Brugat T, Gault N, Vallat L, Kruhoffer M, Orntoft TF, Nguyen-Khac F, Chevillard S, Merle-Beral H, Delic J.
Concomitant heterochromatinisation and down-regulation of gene expression unveils epigenetic silencing of RELB in an aggressive subset of chronic lymphocytic leukemia in males.
BMC Med Genomics. 2010 Nov 10;3(1):53. [Epub ahead of print] PubMed

Modin C, Bjerregaard B, Ørntoft T, Høgdall E; Faglig Følgegruppe for Dansk CancerBiobank.
[Establishing the Danish CancerBiobank]
Ugeskr Laeger. 2010 May 10;172(19):1446-50. Danish. PubMed

Moore F, Naamane N, Colli ML, Bouckenooghe T, Ortis F, Gurzov EN, Igoillo-Esteve M, Mathieu C, Bontempi G, Thykjaer T, Orntoft TF, Eizirik DL
STAT1 is a master regulator of pancreatic beta cells apoptosis and islet inflammation.
J Biol Chem. 2011 Jan 14;286(2):929-41. Epub 2010 Oct 27. PubMed

Niittymäki I, Gylfe A, Laine L, Laakso M, Lehtonen HJ, Kondelin J, Tolvanen J, Nousiainen K, Pouwels J, Järvinen H, Nuorva K, Mecklin JP, Mäkinen M, Ristimäki A, Orntoft TF, Hautaniemi S, Karhu A, Kallio MJ, Aaltonen LA.
High frequency of TTK mutations in microsatellite-unstable colorectal cancer and evaluation of their effect on spindle-assembly checkpoint.
Carcinogenesis. 2011 Mar;32(3):305-11. Epub 2010 Dec 16. PubMed

Out AA, Tops CM, Nielsen M, Weiss MM, van Minderhout IJ, Fokkema IF, Buisine MP, Claes K, Colas C, Fodde R, Fostira F, Franken PF, Gaustadnes M, Heinimann K, Hodgson SV, Hogervorst FB, Holinski-Feder E, Lagerstedt-Robinson K, Olschwang S, van den Ouweland AM, Redeker EJ, Scott RJ, Vankeirsbilck B, Grønlund RV, Wijnen JT, Wikman FP, Aretz S, Sampson JR, Devilee P, den Dunnen JT, Hes FJ.
Leiden Open Variation Database of the MUTYH gene.
Hum Mutat. 2010 Nov;31(11):1205-15. PubMed

Skovby F, Gaustadnes M, Mudd SH.
A revisit to the natural history of homocystinuria due to cystathionine beta-synthase deficiency
Mol Genet Metab. 2010 Jan;99(1):1-3. PubMed

Sørensen KD, Orntoft TF.
Discovery of prostate cancer biomarkers by microarray gene expression profiling.
Expert Rev Mol Diagn. 2010 Jan;10(1):49-64. PubMed

Thorsen K, Mansilla F, Schepeler T, Oster B, Rasmussen MH, Dyrskjot L, Karni R, Akerman M, Krainer AR, Laurberg S, Andersen CL, Orntoft TF
Alternative splicing of SLC39A14 in colorectal cancer is regulated by the Wnt pathway.
Mol Cell Proteomics. 2011 Jan;10(1):M110.002998. Epub 2010 Oct 11. PubMed

Vestergaard EM, Nexø E, Tørring N, Borre M, Orntoft TF, Sørensen KD.
Promoter hypomethylation and upregulation of trefoil factors in prostate cancer.
Int J Cancer. Int J Cancer. 2010 Oct 15;127(8):1857-65. PubMed